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Prosaposin 抗体

The 兔 多克隆 anti-Prosaposin antibody is suitable to detect Prosaposin in samples from 人. It has been validated for WB, IHC (p) 和 IHC (fro).
产品编号 ABIN2854916
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Prosaposin 抗体 (ABIN2854916)

抗原

See all Prosaposin (PSAP) 抗体
Prosaposin (PSAP)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prosaposin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit polyclonal antibody to PSAP (prosaposin)
    PSAP antibody [N1N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human PSAP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: mouse brain , rat brain , HeLa

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.98 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Prosaposin (PSAP)

    别名

    prosaposin

    背景

    This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Cellular Localization: Lysosome

    分子量

    58 kDa

    基因ID

    5660

    UniProt

    P07602

    途径

    Positive Regulation of Endopeptidase Activity
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