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PRNP 抗体

This anti-PRNP antibody is a 兔 多克隆 antibody detecting PRNP in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854915
发货至: 中国

Quick Overview for PRNP 抗体 (ABIN2854915)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRNP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to PRP (prion protein)
    PRP antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Prion Protein (PrP). The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Neuro2A , NIH-3T3 , C2C12 , IMR32

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.36 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    prion protein

    背景

    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.

    Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Golgi apparatus

    分子量

    28 kDa

    基因ID

    5621

    UniProt

    P04156, F7VJQ1

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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