SNRPE 抗体 (Internal Region)
Quick Overview for SNRPE 抗体 (Internal Region) (ABIN2854894)
抗原
See all SNRPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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产品特性
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Rabbit polyclonal antibody to B-Raf (v-raf murine sarcoma viral oncogene homolog B1)
B-Raf antibody [N2C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:10000*
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说明
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Positive Control: A549 , H1299 , HCT116 , PC-12
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
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别名
- B-Raf
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背景
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This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Cellular Localization: Cytoplasm -
分子量
- 84 kDa
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基因ID
- 673
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途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
抗原
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