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Cyclin B1 抗体

This anti-Cyclin B1 antibody is a 兔 多克隆 antibody detecting Cyclin B1 in WB, IF, IHC (p) 和 ICC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2854892
发货至: 中国

Quick Overview for Cyclin B1 抗体 (ABIN2854892)

抗原

See all Cyclin B1 (CCNB1) 抗体
Cyclin B1 (CCNB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Cyclin B1 (cyclin B1)
    Cyclin B1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Cyclin B1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Luo, Liao, Liao, Chen, Huang, Fan, Liao: "The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma." in: World journal of surgical oncology, Vol. 16, Issue 1, pp. 36, (2018) (PubMed).

    Kuo, Li, Stark, Shih, Ann: "RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).

    Li, Wu, Lee, Li, Hsieh, Ho, Ho, Chen, Wang, Yen, Yang, Chen: "Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e104203, (2015) (PubMed).

  • 抗原

    Cyclin B1 (CCNB1)

    别名

    cyclin B1

    背景

    The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

    Cellular Localization: Cytoplasm , Nucleus , Centrosome

    分子量

    48 kDa

    基因ID

    891

    UniProt

    P14635

    途径

    Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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