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Granulin 抗体 (Center)

This anti-Granulin antibody is a 兔 多克隆 antibody detecting Granulin in WB, ICC, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2854868
发货至: 中国

Quick Overview for Granulin 抗体 (Center) (ABIN2854868)

抗原

See all Granulin (GRN) 抗体
Granulin (GRN)

适用

  • 58
  • 11
  • 5
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人, 小鼠, 大鼠

宿主

  • 52
  • 11
  • 5
  • 2
  • 1

克隆类型

  • 57
  • 14
多克隆

标记

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  • 1
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  • 1
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This Granulin antibody is un-conjugated

应用范围

  • 64
  • 30
  • 20
  • 19
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  • 13
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  • 6
  • 6
  • 3
  • 3
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
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    • 4
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    • 3
    • 2
    • 2
    • 2
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    • 1
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    Center

    产品特性

    Rabbit Polyclonal antibody to Granulins (granulin)
    Granulins antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Granulins. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: HepG2 , mouse kidney , rat kidney

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.48 mg/mL

    缓冲液

    1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Granulin (GRN)

    别名

    Granulins

    物质类

    Viral Protein

    背景

    Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

    Cellular Localization: Secreted

    分子量

    64 kDa

    基因ID

    2896
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