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RRM1 抗体 (Center)

This anti-RRM1 antibody is a 兔 多克隆 antibody detecting RRM1 in WB, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN2854856
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RRM1 抗体 (Center) (ABIN2854856)

抗原

See all RRM1 抗体
RRM1 (Ribonucleotide Reductase M1 (RRM1))

适用

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宿主

  • 92
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克隆类型

  • 70
  • 29
多克隆

标记

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This RRM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 11
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    Center

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to RRM1 (ribonucleotide reductase M1)
    RRM1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: NIH-3T3 , Raw264.7 , C2C12

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.49 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    RRM1 (Ribonucleotide Reductase M1 (RRM1))

    别名

    ribonucleotide reductase M1

    背景

    This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

    Cellular Localization: Cytoplasm

    分子量

    90 kDa

    基因ID

    6240

    UniProt

    P23921

    途径

    Positive Regulation of Endopeptidase Activity
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