RRM1 抗体 (Center)
Quick Overview for RRM1 抗体 (Center) (ABIN2854856)
抗原
See all RRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to RRM1 (ribonucleotide reductase M1)
RRM1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibody
RRM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D6D8 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 1-213) antibodyRRM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibodyRRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G5 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 733-778) antibodyRRM1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Internal Region) antibodyRRM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3D6H5 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3 , Raw264.7 , C2C12
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.49 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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别名
- ribonucleotide reductase M1
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背景
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This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Cellular Localization: Cytoplasm -
分子量
- 90 kDa
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基因ID
- 6240
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UniProt
- P23921
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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