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RASSF1 抗体 (Center)

This anti-RASSF1 antibody is a 兔 多克隆 antibody detecting RASSF1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN2854789
发货至: 中国

Quick Overview for RASSF1 抗体 (Center) (ABIN2854789)

抗原

See all RASSF1 抗体
RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RASSF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    Center

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Mouse (91 %), Rat (91 %)

    产品特性

    Rabbit polyclonal antibody to RASSF1 (Ras association (RalGDS/AF-6) domain family member 1)
    RASSF1 antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human RASSF1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , HeLaS3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

    别名

    RASSF1

    背景

    This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    Cellular Localization: Isoform A: Cytoplasm , cytoskeleton , Centrosome , Spindle , Isoform C: Nucleus

    分子量

    39 kDa

    基因ID

    11186
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