Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Center) 抗体
(1 reference)Quick Overview for Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Center) 抗体 (ABIN2854769)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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产品特性
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Rabbit Polyclonal antibody to ACADM (acyl-CoA dehydrogenase, C-4 to C-12 straight chain)
ACADM antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ACADM. The exact sequence is proprietary.
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亚型
- IgG
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anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-421) antibody
MCAD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-421) antibodyMCAD 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-220) antibodyMCAD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) antibodyMCAD 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (C-Term) antibodyMCAD 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 131-421) antibodyMCAD 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 189-217) antibodyMCAD 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20911 unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 196-225) antibodyMCAD 适用: 人, 小鼠 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 26-421) antibodyMCAD 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-100) antibodyMCAD 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: Molt-4 , Neuro2A , GL261 , C8D30 , PC-12
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.55 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain." in: Journal of neurochemistry, Vol. 142, Issue 3, pp. 407-419, (2017) (PubMed).
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: "Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain." in: Journal of neurochemistry, Vol. 142, Issue 3, pp. 407-419, (2017) (PubMed).
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- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)
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别名
- ACADM
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背景
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This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Mitochondrion matrix -
分子量
- 47 kDa
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基因ID
- 34
抗原
-
