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PLAUR 抗体

This anti-PLAUR antibody is a 兔 多克隆 antibody detecting PLAUR in WB, ICC, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN2854760
发货至: 中国

Quick Overview for PLAUR 抗体 (ABIN2854760)

抗原

See all PLAUR 抗体
PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLAUR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to uPAR (plasminogen activator, urokinase receptor)
    uPAR antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human uPAR. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG , HeLa

    Validation: Comparison, KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.34 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

    别名

    plasminogen activator, urokinase receptor

    背景

    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

    Cellular Localization: Isoform 1: Cell membrane, Lipid-anchor , GPI-anchor , Isoform 2: Secreted

    分子量

    37 kDa

    基因ID

    5329

    UniProt

    Q03405

    途径

    Inositol Metabolic Process
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