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GALR2 抗体 (C-Term)

This anti-GALR2 antibody (ABIN2854711) is a Rabbit Polyclonal antibody detecting GALR2 in WB, IHC (p), IF, ICC. Suitable for Human.
产品编号 ABIN2854711
发货至: 中国

Quick Overview for GALR2 抗体 (C-Term) (ABIN2854711)

抗原

See all GALR2 抗体
GALR2 (Galanin Receptor 2 (GALR2))

适用

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宿主

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克隆类型

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多克隆

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This GALR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)
    Galanin Receptor 2 antibody [C1C2], Internal

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GALR2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GALR2 (Galanin Receptor 2 (GALR2))

    别名

    galanin receptor 2

    背景

    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.

    Cellular Localization: Cell membrane, Multi-pass membrane protein

    分子量

    42 kDa

    基因ID

    8811

    UniProt

    O43603

    途径

    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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