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GSTM1 抗体 (C-Term)

This anti-GSTM1 antibody is a 兔 多克隆 antibody detecting GSTM1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854700
发货至: 中国

Quick Overview for GSTM1 抗体 (C-Term) (ABIN2854700)

抗原

See all GSTM1 抗体
GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to GSTM1 (glutathione S-transferase mu 1)
    GSTM1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GSTM1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

    别名

    glutathione S-transferase mu 1

    背景

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

    Cellular Localization: Cytoplasm

    分子量

    26 kDa

    基因ID

    2944

    UniProt

    P09488

    途径

    Negative Regulation of Transporter Activity
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