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HRH3 抗体 (C-Term)

This anti-HRH3 antibody is a 兔 多克隆 antibody detecting HRH3 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854644
发货至: 中国

Quick Overview for HRH3 抗体 (C-Term) (ABIN2854644)

抗原

See all HRH3 抗体
HRH3 (Histamine Receptor H3 (HRH3))

适用

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宿主

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克隆类型

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多克隆

标记

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This HRH3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to Histamine H3 Receptor (histamine receptor H3)
    Histamine H3 Receptor antibody

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Histamine H3 Receptor. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

  • 抗原

    HRH3 (Histamine Receptor H3 (HRH3))

    别名

    histamine receptor H3

    背景

    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

    Cellular Localization: Cell membrane, Multi-pass membrane protein

    分子量

    49 kDa

    基因ID

    11255

    UniProt

    Q9Y5N1

    途径

    cAMP Metabolic Process, Feeding Behaviour
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