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LGI1 抗体

This anti-LGI1 antibody is a 兔 多克隆 antibody detecting LGI1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN2854526
发货至: 中国

Quick Overview for LGI1 抗体 (ABIN2854526)

抗原

See all LGI1 抗体
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LGI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    人, 大鼠

    产品特性

    Rabbit polyclonal antibody to LGI1 (leucine-rich, glioma inactivated 1)
    LGI1 antibody [N2C2], Internal

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human LGI1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , U87-MG , SK-N-SH , SK-N-AS , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    别名

    leucine rich glioma inactivated 1

    背景

    This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

    Cellular Localization: Secreted

    分子量

    64 kDa

    基因ID

    9211

    UniProt

    O95970
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