LGI1 抗体
Quick Overview for LGI1 抗体 (ABIN2854526)
抗原
See all LGI1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            交叉反应
- 人, 大鼠
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                                            产品特性
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                        Rabbit polyclonal antibody to LGI1 (leucine-rich, glioma inactivated 1)
 LGI1 antibody [N2C2], Internal
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Recombinant protein encompassing a sequence within the center region of human LGI1. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: A431 , U87-MG , SK-N-SH , SK-N-AS , rat brain 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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                                            别名
- leucine rich glioma inactivated 1
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                                            背景
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                        This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. 
 Cellular Localization: Secreted
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                                            分子量
- 64 kDa
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                                            基因ID
- 9211
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                                            UniProt
- O95970
 抗原
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