Bestrophin 1 抗体
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北京 101111
Quick Overview for Bestrophin 1 抗体 (ABIN2854513)
抗原
See all Bestrophin 1 (BEST1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Bestrophin 1 (bestrophin 1)
Bestrophin 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Bestrophin 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Bestrophin 1 (BEST1) (AA 200-300) antibody
BEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) antibodyBEST1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 1-604) antibodyBEST1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 259-270), (Extracellular) antibodyBEST1 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 376-585) antibodyBEST1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bestrophin 1 (BEST1) (AA 361-460) antibodyBEST1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Bestrophin 1 (BEST1) (AA 292-585) antibodyBEST1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NT2D1 , PC-3 , SK-N-SH
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Bestrophin 1 (BEST1)
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别名
- bestrophin 1
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背景
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This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Cellular Localization: Cell membrane -
分子量
- 68 kDa
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基因ID
- 7439
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UniProt
- O76090
抗原
-
