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METTL3 抗体

This anti-METTL3 antibody is a 兔 多克隆 antibody detecting METTL3 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854497
发货至: 中国

Quick Overview for METTL3 抗体 (ABIN2854497)

抗原

See all METTL3 抗体
METTL3 (Methyltransferase Like 3 (METTL3))

适用

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宿主

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克隆类型

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多克隆

标记

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This METTL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 大鼠

    产品特性

    Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)
    METTL3 antibody [N2C2], Internal

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Molt-4

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liang, Guan, Lin, Li, Geng, Li: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." in: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).

  • 抗原

    METTL3 (Methyltransferase Like 3 (METTL3))

    别名

    methyltransferase like 3

    背景

    This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

    Cellular Localization: Nucleus speckle

    分子量

    64 kDa

    基因ID

    56339

    UniProt

    Q86U44
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