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DUSP14 抗体 (C-Term)

This anti-DUSP14 antibody is a 兔 多克隆 antibody detecting DUSP14 in WB. Suitable for 人.
产品编号 ABIN2854481
发货至: 中国

Quick Overview for DUSP14 抗体 (C-Term) (ABIN2854481)

抗原

See all DUSP14 抗体
DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

适用

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宿主

  • 36
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克隆类型

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多克隆

标记

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This DUSP14 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 7
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    C-Term

    交叉反应

    产品特性

    Rabbit polyclonal antibody to MKP-6 (dual specificity phosphatase 14)
    MKP-6 antibody [C2C3], C-term

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP14. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MKP-6 transfected 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

    别名

    dual specificity phosphatase 14

    背景

    In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80, MIM 112203) and B7-2 (CD86, MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2, MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4, MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM]

    分子量

    22 kDa

    基因ID

    11072

    UniProt

    O95147
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