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ALAS2 抗体 (Center)

This anti-ALAS2 antibody is a 兔 多克隆 antibody detecting ALAS2 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2854459
发货至: 中国

Quick Overview for ALAS2 抗体 (Center) (ABIN2854459)

抗原

See all ALAS2 抗体
ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

适用

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人, 小鼠

宿主

  • 48
  • 9

克隆类型

  • 47
  • 10
多克隆

标记

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This ALAS2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Center

    交叉反应

    大鼠, 非洲爪蟾, 斑马鱼, 牛, Xenopus tropicalis

    交叉反应 (详细)

    Rat (95 %), Xenopus laevis (81 %), Zebrafish (80 %), Bovine (95 %), Xenopus tropicalis (81 %)

    产品特性

    Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)
    ALAS-E antibody [N3C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: Raji , K562 , HL60 , mouse liver

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Vercellotti, Khan, Nguyen, Chen, Bruzzone, Bechtel, Brown, Nath, Steer, Hebbel, Belcher: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).

  • 抗原

    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

    别名

    ALAS-E

    背景

    The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Mitochondrion matrix

    分子量

    65 kDa

    基因ID

    212

    途径

    Transition Metal Ion Homeostasis
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