ENPP1 抗体
Quick Overview for ENPP1 抗体 (ABIN2854438)
抗原
See all ENPP1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1)
ENPP1 antibody [N2C2], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ENPP1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2 , human liver
Validation: KO/KD, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.14 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate." in: Nature communications, Vol. 8, pp. 14706, (2018) (PubMed).
: "
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Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate." in: Nature communications, Vol. 8, pp. 14706, (2018) (PubMed).
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- ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
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别名
- ectonucleotide pyrophosphatase/phosphodiesterase 1
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背景
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This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
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分子量
- 105 kDa
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基因ID
- 5167
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UniProt
- P22413
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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