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IL5RA 抗体

This anti-IL5RA antibody is a 兔 多克隆 antibody detecting IL5RA in WB. Suitable for 人.
产品编号 ABIN2854437
发货至: 中国

Quick Overview for IL5RA 抗体 (ABIN2854437)

抗原

See all IL5RA 抗体
IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

适用

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宿主

  • 71
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克隆类型

  • 70
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多克隆

标记

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This IL5RA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to IL5 Receptor alpha (interleukin 5 receptor, alpha)
    IL5 Receptor alpha antibody [N1C2]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human IL5 Receptor alpha. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

    别名

    interleukin 5 receptor subunit alpha

    背景

    The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    分子量

    48 kDa

    基因ID

    3568

    UniProt

    Q01344

    途径

    JAK/STAT Signaling
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