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ZAK 抗体

KO Validated ZAK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854433
发货至: 中国
  • 抗原 See all ZAK 抗体
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    适用
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    宿主
    • 51
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    克隆类型
    • 51
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    多克隆
    标记
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    This ZAK antibody is un-conjugated
    应用范围
    • 30
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to ZAK
    ZAK antibody [N3C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ZAK. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ZAK Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HeLa

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.92 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    别名
    mitogen-activated protein kinase kinase kinase 20 (ZAK 产品)
    别名
    MLTK antibody, RGD1561394 antibody, AZK antibody, MLK7 antibody, MLT antibody, MRK antibody, mlklak antibody, pk antibody, AV006891 antibody, B230120H23Rik antibody, MLTKalpha antibody, MLTKbeta antibody, mitogen-activated protein kinase kinase kinase 20 antibody, Map3k20 antibody, MAP3K20 antibody
    背景
    This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Cytoplasm , Nucleus
    分子量
    91 kDa
    基因ID
    51776
    UniProt
    Q9NYL2
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