Quick Overview for ZAK 抗体 (ABIN2854433)
抗原
See all ZAK 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to ZAK
ZAK antibody [N3C2], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ZAK. The exact sequence is proprietary.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-120) antibody
ZAK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-330) antibodyZAK 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-120) antibodyZAK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-455) antibodyZAK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) antibodyZAK 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-455) antibodyZAK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-120) antibodyZAK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (N-Term) antibodyZAK 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 100-312) antibodyZAK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 271-300) antibodyZAK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03313-03314 unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.92 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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别名
- mitogen-activated protein kinase kinase kinase 20
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背景
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This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 91 kDa
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基因ID
- 51776
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UniProt
- Q9NYL2
抗原
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