CRYGC 抗体
Quick Overview for CRYGC 抗体 (ABIN2854417)
抗原
See all CRYGC 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to Gamma-crystallin C (crystallin, gamma C)
gamma C Crystallin antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human gamma C Crystallin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Crystallin, gamma C (CRYGC) (AA 1-174) antibody
CRYGC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma C (CRYGC) (AA 75-174) antibodyCRYGC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7C4 unconjugated
anti-Crystallin, gamma C (CRYGC) (AA 71-120) antibodyCRYGC 适用: 人, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma C (CRYGC) antibodyCRYGC 适用: 人 WB 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Crystallin, gamma C (CRYGC) (Middle Region) antibodyCRYGC 适用: 人, 大鼠, 兔, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , mouse eye
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CRYGC (Crystallin, gamma C (CRYGC))
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别名
- crystallin gamma C
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背景
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Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
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分子量
- 21 kDa
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基因ID
- 1420
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UniProt
- P07315
抗原
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