电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Aconitase 1 抗体

This anti-Aconitase 1 antibody is a 兔 多克隆 antibody detecting Aconitase 1 in WB, ICC 和 IF. Suitable for 人.
产品编号 ABIN2854415
发货至: 中国

Quick Overview for Aconitase 1 抗体 (ABIN2854415)

抗原

See all Aconitase 1 (ACO1) 抗体
Aconitase 1 (ACO1)

适用

  • 108
  • 54
  • 46
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 119
  • 4
  • 1

克隆类型

  • 119
  • 5
多克隆

标记

  • 58
  • 14
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aconitase 1 antibody is un-conjugated

应用范围

  • 108
  • 39
  • 35
  • 33
  • 26
  • 25
  • 21
  • 16
  • 11
  • 10
  • 7
  • 3
  • 2
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to Aconitase 1 (aconitase 1, soluble)
    Aconitase 1 antibody [N1C1]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Aconitase 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , HeLa , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.78 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Aconitase 1 (ACO1)

    别名

    aconitase 1

    背景

    Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

    Cellular Localization: Cytoplasm

    分子量

    98 kDa

    基因ID

    48

    UniProt

    P21399

    途径

    Transition Metal Ion Homeostasis
You are here:
Chat with us!