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E2F3 抗体

KO Validated 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854385
发货至: 中国
  • 抗原 See all E2F3 抗体
    E2F3
    适用
    • 65
    • 59
    • 38
    • 3
    • 3
    • 3
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    • 2
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    • 2
    • 1
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    • 1
    宿主
    • 80
    • 4
    • 1
    克隆类型
    • 82
    • 3
    多克隆
    标记
    • 27
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    • 3
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    • 3
    • 3
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    This E2F3 antibody is un-conjugated
    应用范围
    • 79
    • 39
    • 39
    • 38
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Knockdown/Knockout validation was supported by customer review data.
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to E2F3 (E2F transcription factor 3)
    E2F3 antibody [N2C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human E2F3. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product E2F3 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.28 mg/mL
    缓冲液
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    E2F3
    别名
    E2F transcription factor 3 (E2F3 产品)
    别名
    E2F-3 antibody, E2F3b antibody, E2f3a antibody, mKIAA0075 antibody, RGD1561600 antibody, E2F transcription factor 3 antibody, E2F transcription factor 3 S homeolog antibody, E2F3 antibody, e2f3.S antibody, E2f3 antibody
    背景
    The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.

    分子量
    49 kDa
    基因ID
    1871
    UniProt
    O00716
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