E2F3 抗体
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北京 101111
Quick Overview for E2F3 抗体 (ABIN2854385)
抗原
See all E2F3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- Knockdown/Knockout validation was supported by customer review data.
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to E2F3 (E2F transcription factor 3)
E2F3 antibody [N2C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human E2F3. The exact sequence is proprietary.
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亚型
- IgG
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anti-E2F3 (AA 336-425) antibody
适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 5F7 unconjugated
anti-E2F3 (C-Term) antibody适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (AA 381-465) antibody适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (C-Term) antibody适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat, Pig, Hamster WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (acLys168) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (AA 200-300) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (AA 1-108) antibody适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-E2F3 (C-Term) antibodyVerified 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-E2F3 (AA 1-133) antibody适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-E2F3 (AA 1-133) antibody适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.28 mg/mL
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缓冲液
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- E2F3
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别名
- E2F transcription factor 3
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背景
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The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
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分子量
- 49 kDa
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基因ID
- 1871
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UniProt
- O00716
抗原
-
