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CRH 抗体

CRH 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854316
发货至: 中国
  • 抗原 See all CRH 抗体
    CRH (Corticotropin Releasing Hormone (CRH))
    适用
    • 76
    • 52
    • 50
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    宿主
    • 84
    • 18
    • 2
    • 2
    克隆类型
    • 90
    • 16
    多克隆
    标记
    • 43
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    • 6
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    • 2
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    This CRH antibody is un-conjugated
    应用范围
    • 82
    • 36
    • 29
    • 26
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    • 13
    • 9
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    • 6
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    • 5
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to CRF (corticotropin releasing hormone)
    CRF antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CRF. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product CRH Primary Antibody
  • 应用备注
    IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.17 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    CRH (Corticotropin Releasing Hormone (CRH))
    别名
    corticotropin releasing hormone (CRH 产品)
    别名
    CRF antibody, Gm1347 antibody, crf antibody, crh antibody, zgc:101864 antibody, CRH antibody, corticoliberin antibody, crhb antibody, crh.1-a antibody, crha antibody, corticotropin releasing hormone antibody, corticotropin releasing hormone b antibody, corticotropin releasing hormone S homeolog antibody, corticotropin releasing hormone L homeolog antibody, Crh antibody, CRH antibody, crhb antibody, crh antibody, crh.S antibody, crh.L antibody
    背景
    Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition.

    Cellular Localization: Secreted
    分子量
    21 kDa
    基因ID
    1392
    UniProt
    P06850
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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