CD52 抗体 (PE)

CD52抗体详情 (hide)

抗原 See all CD52 抗体

CD52

适用 All reactivities for CD52 抗体

• Human 51
• Monkey 11
• Rhesus Monkey 7
• Cynomolgus 5
• Mouse 5
• Rat 1

小鼠

宿主 All hosts for CD52 抗体

• Rabbit 22
• Rat 18
• Mouse 14
• Human 1

大鼠

Compatible Secondaries

克隆类型 All clonalities for CD52 抗体

• Monoclonal 34
• Polyclonal 13
• Chimeric 5

单克隆

标记 All conjugates for CD52 抗体

• 非结合性 33
• FITC 6
• PE 4
• Biotin 3
• APC 2
• Alexa Fluor 488 1
• Alexa Fluor 555 1
• Alexa Fluor 594 1
• Alexa Fluor 647 1
• Alexa Fluor 680 1
• Alexa Fluor 750 1
• CF-Blue 1

This CD52 antibody is conjugated to PE

应用范围 All applications for CD52 抗体

• Flow Cytometry (FACS) 38
• Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21
• Western Blotting (WB) 21
• Immunohistochemistry (Frozen Sections) (IHC (fro)) 16
• Cytotoxicity Test (CyTox) 14
• ELISA 13
• Immunohistochemistry (IHC) 11
• Immunoprecipitation (IP) 9
• Immunofluorescence (IF) 5
• In vivo Studies (in vivo) 5
• Enzyme Immunoassay (EIA) 2
• Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2
• Immunohistochemistry (Resin Sections) (IHC (rs)) 1
• DNA Microscopy (DNA Mic) 1

Flow Cytometry (FACS)

特异性

This antibody reacts with mouse CD52 antigen.

纯化方法

Protein G agarose

免疫原

IL-2Ralpha-transgenic mouse splenocyte

克隆位点

BTG-2G

亚型

IgG2a

Alternatives (show)

anti-CD52 (CD52) antibody

CD52 适用: 人, 猕猴, Cynomolgus FACS, WB, IHC (p), ELISA, IHC (fro), CyTox, in vivo 宿主: Human Monoclonal Campath-1H unconjugated Recombinant Antibody

anti-CD52 (CD52) (AA 29-48) antibody

CD52 适用: 小鼠 WB, IHC (p), IP, IF 宿主: 兔 Polyclonal unconjugated

anti-CD52 (CD52) (AA 1-61) antibody

CD52 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD52 (CD52) (AA 20-50) antibody

CD52 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-CD52 (CD52) antibody

CD52 适用: 人, 猕猴, Cynomolgus FACS, WB, IHC (p), ELISA, IHC (fro), CyTox, in vivo 宿主: 兔 Chimeric Campath-1H unconjugated Recombinant Antibody

anti-CD52 (CD52) antibody

CD52 适用: 人 IHC (f) 宿主: 兔 Monoclonal CD52-2276R unconjugated Recombinant Antibody

anti-CD52 (CD52) antibody

CD52 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal BTG-2G unconjugated

anti-CD52 (CD52) antibody (FITC)

GMP Grade CD52 适用: 人 FACS 宿主: 小鼠 Monoclonal CF-1D12 FITC

anti-CD52 (CD52) antibody

CD52 适用: 人 FACS, IHC (p), DNA Mic 宿主: 小鼠 Monoclonal HI186 unconjugated

anti-CD52 (CD52) antibody (APC)

CD52 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal HI186 APC

使用细节 (hide)

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用

贮存及处理 (hide)

缓冲液

50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3

储存条件

4 °C

储存方法

Store at 2-8 °C.

CD52目标详情 (hide)

抗原

CD52

别名

CD52 / CAMPATH-1 (CD52 产品)

别名

CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody

背景

CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

基因ID

23833

NCBI登录号

NP_038734

UniProt

Q64389