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CD52 抗体 (PE)

CD52 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal BTG-2G PE
产品编号 ABIN2853610
发货至: 中国
  • 抗原 See all CD52 抗体
    CD52
    适用
    • 60
    • 11
    • 7
    • 5
    • 4
    • 1
    小鼠
    宿主
    • 23
    • 19
    • 19
    • 1
    • 1
    大鼠
    克隆类型
    • 46
    • 11
    • 3
    单克隆
    标记
    • 33
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD52 antibody is conjugated to PE
    应用范围
    • 48
    • 20
    • 19
    • 16
    • 14
    • 13
    • 12
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody reacts with mouse CD52 antigen.
    纯化方法
    Protein G agarose
    免疫原
    IL-2Ralpha-transgenic mouse splenocyte
    克隆位点
    BTG-2G
    亚型
    IgG2a
    Top Product
    Discover our top product CD52 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    CD52
    别名
    CD52 / CAMPATH-1 (CD52 产品)
    背景
    CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
    基因ID
    23833
    NCBI登录号
    NP_038734
    UniProt
    Q64389
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