CD52 抗体 (PE)
Quick Overview for CD52 抗体 (PE) (ABIN2853610)
抗原
See all CD52 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            特异性
- This antibody reacts with mouse CD52 antigen.
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                                            纯化方法
- Protein G agarose
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                                            免疫原
- IL-2Ralpha-transgenic mouse splenocyte
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                                            亚型
- IgG2a
 
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    - 
                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            限制
- 仅限研究用
 
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    - 
                                            缓冲液
- 50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3
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                                            储存条件
- 4 °C
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                                            储存方法
- Store at 2-8 °C.
 
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    - CD52
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                                            别名
- CD52 / CAMPATH-1
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                                            背景
- CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
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                                            基因ID
- 23833
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                                            NCBI登录号
- NP_038734
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                                            UniProt
- Q64389
 抗原
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