CD52 抗体 (PE)
Quick Overview for CD52 抗体 (PE) (ABIN2853610)
抗原
See all CD52 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody reacts with mouse CD52 antigen.
-
纯化方法
- Protein G agarose
-
免疫原
- IL-2Ralpha-transgenic mouse splenocyte
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- 50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8 °C.
-
-
- CD52
-
别名
- CD52 / CAMPATH-1
-
背景
- CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
-
基因ID
- 23833
-
NCBI登录号
- NP_038734
-
UniProt
- Q64389
抗原
-