DLK1 抗体 (FITC)
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Quick Overview for DLK1 抗体 (FITC) (ABIN2853604)
抗原
See all DLK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Dlk.
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交叉反应 (详细)
- Species reactivity (tested):Mouse.
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纯化方法
- Protein G Agarose Chromatography of hybridoma supernatant
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免疫原
- Pref-1-Fc protein
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C.
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- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
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别名
- DLK1
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背景
- Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2
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基因ID
- 13386
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NCBI登录号
- NP_034182
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UniProt
- Q09163
抗原
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