Protease 抗体
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北京 101111
Quick Overview for Protease 抗体 (ABIN284976)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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纯度
- > 95 % pure
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免疫原
- HIV1 protease antibody was raised in rabbit using full length recombinant protease (HIV-1) as the immunogen.
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亚型
- IgG
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应用备注
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ELISA: 1:500-1:1,000, WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Frozen
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浓度
- Lot specific
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缓冲液
- Supplied frozen in PBS.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.
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- Protease
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物质类
- Viral Protein
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背景
- HIV-1 protease (HIV PR) is a retroviral aspartyl protease that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV PR cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV PR, HIV virions remain uninfectious. Thus, mutation of HIV PR’s active site or inhibition of its activity disrupts HIV’s ability to replicate and infect additional cells, making HIV PR inhibition the subject of much pharmaceutical research.
抗原
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