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KLF4 抗体 (N-Term)

This anti-KLF4 antibody is a 兔 多克隆 antibody detecting KLF4 in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN389188
发货至: 中国

Quick Overview for KLF4 抗体 (N-Term) (ABIN389188)

抗原

See all KLF4 抗体
KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

适用

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宿主

  • 93
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克隆类型

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多克隆

标记

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This KLF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB14261
  • 抗原表位

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    AA 20-53, N-Term

    特异性

    This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20~50 amino acids from the N-terminal region of human KLF4.

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-53 AA from the N-terminal region of human KLF4.

    亚型

    Ig Fraction
  • 应用备注

    WB = 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Xu, Sun, Zhang, Jiang, Zhang, Zhou, Ding, Hu, Yan: "MicroRNA-145 protects follicular granulosa cells against oxidative stress-induced apoptosis by targeting Krüppel-like factor 4." in: Molecular and cellular endocrinology, Vol. 452, pp. 138-147, (2018) (PubMed).

    Yan, Yu, Liu, Kang, Ma, Zhou: "MiR-32 promotes gastric carcinoma tumorigenesis by targeting Kruppel-like factor 4." in: Biochemical and biophysical research communications, Vol. 467, Issue 4, pp. 913-20, (2015) (PubMed).

    Jumabay, Abdmaulen, Ly, Cubberly, Shahmirian, Heydarkhan-Hagvall, Dumesic, Yao, Boström: "Pluripotent stem cells derived from mouse and human white mature adipocytes." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 161-71, (2014) (PubMed).

    Marini, Porcu, Asunis, Loi, Ristaldi, Porcu, Ikuta, Cao, Moi: "Regulation of the human HBA genes by KLF4 in erythroid cell lines." in: British journal of haematology, Vol. 149, Issue 5, pp. 748-58, (2010) (PubMed).

  • 抗原

    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

    别名

    KLF4

    背景

    Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
    Synonyms: Kruppel-like factor 4, EZF, GKLF

    分子量

    50945 DA

    基因ID

    9314

    NCBI登录号

    NP_004226

    途径

    Peptide Hormone Metabolism, Stem Cell Maintenance
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