LLGL1+2 (pSer650), (pSer654) 抗体
This 兔 多克隆 antibody specifically detects LLGL1+2 in WB. It exhibits reactivity toward 人.It has been mentioned in 1 publication
(1 reference)
产品编号 ABIN388990
发货至:
中国
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Quick Overview for LLGL1+2 (pSer650), (pSer654) 抗体 (ABIN388990)
抗原
LLGL1+2
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB)
克隆位点
RB7629-RB7630
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抗原表位
- pSer650, pSer654
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预测反应
- Cow (Bovine),Mouse (Murine),Rat (Rattus)
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LLGL1/2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S645/S649 of human LLGL1/2.
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亚型
- Ig Fraction
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应用备注
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Suggested dilutions:
WB = 1:1000
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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: "Myosin IIB deficiency in embryonic fibroblasts affects regulators and core members of the par polarity complex." in: Histochemistry and cell biology, Vol. 136, Issue 3, pp. 245-66, (2011) (PubMed).
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- LLGL1+2
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背景
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Function
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
Cellular Location
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells
Synonyms: Lethal(2) giant larvae protein homolog 2, HGL, LLGL2, Lethal(2) giant larvae protein homolog 1, LLGL, Human homolog to the D-lgl gene, Hugl-1, DLG4, LLGL1, HUGL -
分子量
- 115042 Da
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基因ID
- 3993
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UniProt
- Q6P1M3
抗原
-
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