CBX5 抗体 (pTyr43) (AbBy Fluor® 594)
Quick Overview for CBX5 抗体 (pTyr43) (AbBy Fluor® 594) (ABIN2814480)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr43
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交叉反应 (详细)
- Fruit Fly
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预测反应
- Drosophila
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
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亚型
- IgG
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- HP1
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背景
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Synonyms: Heterochromatin protein 1, HP1, Non-histone chromosomal protein C1A9 antigen, CG8409
Background: HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
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基因ID
- 34119
抗原
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