GDAP1 抗体 (AA 151-230) (AbBy Fluor® 594)
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北京 101111
Quick Overview for GDAP1 抗体 (AA 151-230) (AbBy Fluor® 594) (ABIN2813656)
抗原
See all GDAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-230
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GDAP1
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亚型
- IgG
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anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) antibody
GDAP1 适用: 小鼠, 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) (AA 158-257) antibodyGDAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) (AA 1-225) antibodyGDAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
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别名
- GDAP1
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背景
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Synonyms: Ganglioside induced dferentiation associated protein 1, Ganglioside-induced dferentiation-associated protein 1, GDAP1, GDAP1_HUMAN.
Background: Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.
抗原
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