FBXO36 抗体 (AA 1-100) (AbBy Fluor® 594)
Quick Overview for FBXO36 抗体 (AA 1-100) (AbBy Fluor® 594) (ABIN2813168)
抗原
See all FBXO36 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-100
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog,Cow,Sheep,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human FBXO6
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- FBXO36 (F-Box Protein 36 (FBXO36))
-
别名
- FBXO36
-
背景
-
Synonyms: F box only protein 36, F box protein 36, F-box only protein 36, Fbx 36, Fbx36, FBX36_HUMAN, FBXO 36, Fbxo36, FLJ37592, FLJ41090.
Background: FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and -catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.
-
基因ID
- 130888
-
UniProt
- Q8NEA4
抗原
-