COPS6 抗体 (AbBy Fluor® 594)
Quick Overview for COPS6 抗体 (AbBy Fluor® 594) (ABIN2811863)
抗原
See all COPS6 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COPS6
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亚型
- IgG
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anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibody
COPS6 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibodyCOPS6 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 58-327) antibodyCOPS6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) antibodyCOPS6 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 201-250) antibodyCOPS6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 1-327) antibodyCOPS6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (AA 30-327) antibodyCOPS6 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-COP9 Signalosome Complex Subunit 6 (COPS6) (Middle Region) antibodyCOPS6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
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别名
- COPS6
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背景
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Synonyms: JAB1 containing signalosome subunit 6,COP9 subunit 6 MOV34 homolog, 34 kD,MOV34 homolog, 34 kD,COP9 constitutive photomorphogenic, subunit 6, COP9 complex S6,COP9 signalosome complex subunit 6,COP9 signalosome subunit 6,cops6,CSN6,CSN6_HUMAN,hVIP,JAB1-containing signalosome subunit 6,MOV34 homolog,MOV34-34KD,Sgn3,SGN6,Signalosome subunit 6,VIP/MOV34,Vpr interacting protein,Vpr-interacting protein.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
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基因ID
- 10980
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途径
- Cell Division Cycle
抗原
-
