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CASC3 抗体 (AA 501-600) (AbBy Fluor® 594)

This anti-CASC3 antibody is a 兔 多克隆 antibody detecting CASC3 in WB, IF (p) 和 IF (cc). Suitable for 小鼠.
产品编号 ABIN2811115
发货至: 中国

Quick Overview for CASC3 抗体 (AA 501-600) (AbBy Fluor® 594) (ABIN2811115)

抗原

See all CASC3 抗体
CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

适用

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小鼠

宿主

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  • 1

克隆类型

  • 71
多克隆

标记

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This CASC3 antibody is conjugated to AbBy Fluor® 594

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    AA 501-600

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CASC3/MLN51

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

    别名

    CASC3

    背景

    Synonyms: Barentsz protein, Btz, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51, MLN 51 protein, MLN51, Protein barentsz, Protein CASC3, Protein MLN 51, MLN51, CASC3_HUMAN.

    Background: The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonexon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.

    基因ID

    22794
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