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B-Cell Linker 抗体 (pTyr84) (AbBy Fluor® 594)

This AbBy Fluor® 594-conjugated 兔 多克隆 anti-B-Cell Linker antibody specifically detects B-Cell Linker in WB 和 IF (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2810346
发货至: 中国
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Quick Overview for B-Cell Linker 抗体 (pTyr84) (AbBy Fluor® 594) (ABIN2810346)

抗原

See all B-Cell Linker (BLNK) 抗体
B-Cell Linker (BLNK)

适用

  • 114
  • 84
  • 54
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 124
  • 8
  • 1

克隆类型

  • 113
  • 20
多克隆

标记

  • 53
  • 7
  • 7
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This B-Cell Linker antibody is conjugated to AbBy Fluor® 594

应用范围

  • 120
  • 51
  • 36
  • 28
  • 26
  • 20
  • 19
  • 9
  • 7
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 24
    • 20
    • 17
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr84

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr84 [EM(p-Y)VM]

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    B-Cell Linker (BLNK)

    别名

    BLNK

    背景

    Synonyms: BLNK phospho Y84, p-BLNK phospho Y84, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell linker, B cell linker protein, B cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, BASH, Bca, Bca, BLNK, BLNK s, BLNK_HUMAN, Cytoplasmic adapter protein, Ly 57, Ly-57, Ly57, Lymphocyte antigen 57, Lymphocyte antigen-57, Lyw 57, Lyw-57, Lyw57, MGC111051, SLP 65, SLP65, SLP-65, Src homology 2 domain containing leukocyte protein of 65 kDa.

    Background: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

    基因ID

    29760

    途径

    BCR Signaling
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