AGPS 抗体 (AA 31-130) (AbBy Fluor® 594)
Quick Overview for AGPS 抗体 (AA 31-130) (AbBy Fluor® 594) (ABIN2809544)
抗原
See all AGPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 31-130
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交叉反应
 - 大鼠
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预测反应
 - Human,Mouse,Cow,Pig,Horse
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human AGPS/Alkyl-DHAP synthase
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亚型
 - IgG
 
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应用备注
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                        IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- AGPS (Alkylglycerone Phosphate Synthase (AGPS))
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别名
 - AGPS/Alkyl-DHAP synthase
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背景
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Synonyms: AAG5, ADAP-S, ADAS, ADAS_HUMAN, ADHAPS, ADPS, Aging associated gene 5 protein, Aging-associated gene 5 protein, AGPS, ALDHPSY, Alkyl-DHAP synthase, Alkyldihydroxyacetonephosphate synthase, Alkyldihydroxyacetonephosphate synthase, peroxisomal, Alkylglycerone phosphate synthase, Alkylglycerone-phosphate synthase, peroxisomal.
Background: AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
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基因ID
 - 8540
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途径
 - SARS-CoV-2 Protein Interactome
 
抗原
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