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Uromodulin 抗体 (AA 351-450) (AbBy Fluor® 594)

This anti-Uromodulin antibody is a 兔 多克隆 antibody detecting Uromodulin in WB, FACS, IF (cc) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2807414
发货至: 中国

Quick Overview for Uromodulin 抗体 (AA 351-450) (AbBy Fluor® 594) (ABIN2807414)

抗原

See all Uromodulin (UMOD) 抗体
Uromodulin (UMOD)

适用

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人, 小鼠, 大鼠

宿主

  • 62
  • 16
  • 5
  • 2

克隆类型

  • 71
  • 14
多克隆

标记

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  • 1
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This Uromodulin antibody is conjugated to AbBy Fluor® 594

应用范围

  • 66
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  • 19
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
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    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from Human Uromodulin

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Uromodulin (UMOD)

    别名

    Uromodulin

    背景

    Synonyms: ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, medullary cystic kidney disease 2 autosomal dominant, Tamm Horsfall glycoprotein, Tamm Horsfall urinary glycoprotein, Tamm-Horsfall urinary glycoprotein, THGP, THP, Umod, UROM_HUMAN, Uromodulin.

    Background: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. Uromodulin, secreted form: Secreted into urine after proteolytical cleavage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.

    基因ID

    7369

    UniProt

    P07911
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