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TRIM32 抗体 (AA 301-400) (AbBy Fluor® 594)

This anti-TRIM32 antibody is a 兔 多克隆 antibody detecting TRIM32 in WB, FACS, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN2807199
发货至: 中国

Quick Overview for TRIM32 抗体 (AA 301-400) (AbBy Fluor® 594) (ABIN2807199)

抗原

See all TRIM32 抗体
TRIM32 (Tripartite Motif Containing 32 (TRIM32))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This TRIM32 antibody is conjugated to AbBy Fluor® 594

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 301-400

    交叉反应

    小鼠

    预测反应

    Human,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse TRIM32

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TRIM32 (Tripartite Motif Containing 32 (TRIM32))

    别名

    TRIM32/BBS11

    背景

    Synonyms: 72 kda Tat interacting Protein, BBS11, HT2A, LGMD2H, Limb girdle muscular dystrophy 2H autosomal recessive, Limb girdle muscular dystrophy 2H, Muscular dystrophy Hutterite type, TAT interactive protein 72KD, TATIP, Tripartite Mot Containing Protein 32, Zinc Finger Protein HT2A, TRI32_MOUSE.

    Background: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains, it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.

    基因ID

    22954

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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