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OTX2 抗体 (AA 15-105) (AbBy Fluor® 594)

This anti-OTX2 antibody is a 兔 多克隆 antibody detecting OTX2 in WB, IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN2804926
发货至: 中国

Quick Overview for OTX2 抗体 (AA 15-105) (AbBy Fluor® 594) (ABIN2804926)

抗原

See all OTX2 抗体
OTX2 (Orthodenticle Homeobox 2 (OTX2))

适用

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  • 15
  • 5
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  • 1
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大鼠

宿主

  • 53
  • 4

克隆类型

  • 51
  • 6
多克隆

标记

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  • 4
  • 3
  • 3
  • 1
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  • 1
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This OTX2 antibody is conjugated to AbBy Fluor® 594

应用范围

  • 41
  • 21
  • 14
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  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-105

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OTX2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    OTX2 (Orthodenticle Homeobox 2 (OTX2))

    别名

    OTX2

    背景

    Synonyms: CPHD6, Homeobox protein OTX2, MCOPS 5, MCOPS5, MGC45000, Orthodenticle 2, Orthodenticle homeobox 2, Orthodenticle homolog 2 Drosophila, Orthodenticle homolog 2, Orthodenticle2, Otx 2, otx2, OTX2_HUMAN.

    Background: Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.

    途径

    Dopaminergic Neurogenesis
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