KDM3B 抗体 (AA 1601-1761) (AbBy Fluor® 594)
Quick Overview for KDM3B 抗体 (AA 1601-1761) (AbBy Fluor® 594) (ABIN2803463)
抗原
See all KDM3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1601-1761
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human JMJD1B
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1059-1283) antibody
KDM3B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1601-1761) antibodyKDM3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1-759) antibodyKDM3B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (Internal Region) antibodyKDM3B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1691-1740) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (C-Term) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 非洲爪蟾, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 869-897) antibodyKDM3B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14344 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1328-1358), (C-Term) antibodyKDM3B 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14629 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1335-1358), (C-Term) antibodyKDM3B 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 876-905), (Middle Region) antibodyKDM3B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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别名
- JMJD1B
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背景
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Synonyms: JHDM2B, JmjC domain containing histone demethylation protein 2B, JmjC domain-containing histone demethylation protein 2B , jmjd1b, Jumonji domain containing protein 1B, JUMONJI DOMAIN-CONTAINING PROTEIN 1B , KDM3B, KDM3B_HUMAN, Lysine-specic demethylase 3B, Nuclear protein 5qNCA.
Background: JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
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基因ID
- 51780
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途径
- Warburg Effect
抗原
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