ITM2C 抗体 (AA 3-88) (AbBy Fluor® 594)
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北京 101111
Quick Overview for ITM2C 抗体 (AA 3-88) (AbBy Fluor® 594) (ABIN2803440)
抗原
See all ITM2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-88
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ITM2C
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亚型
- IgG
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anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 绵羊, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ITM2C (Integral Membrane Protein 2C (ITM2C))
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别名
- ITM2C
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背景
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Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.
Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
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基因ID
- 81618
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UniProt
- Q9NQX7
抗原
-
