RanBP3 抗体 (AA 441-540) (Biotin)
Quick Overview for RanBP3 抗体 (AA 441-540) (Biotin) (ABIN2803269)
抗原
See all RanBP3 (RANBP3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 441-540
-
交叉反应
- 小鼠, 大鼠
-
预测反应
- Human,Dog,Pig,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human RanBP3
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
-
别名
- RanBP3
-
背景
-
Synonyms: Ran-binding protein 3, RanBP3
Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
-
基因ID
- 8498
-
UniProt
- Q9H6Z4
抗原
-