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SMYD2A 抗体 (AA 351-433)

SMYD2A 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2803151
发货至: 中国
  • 抗原 See all SMYD2A 抗体
    SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
    抗原表位
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-433
    适用
    • 42
    • 28
    • 15
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 4
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This SMYD2A antibody is un-conjugated
    应用范围
    • 22
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SMYD2
    亚型
    IgG
    Top Product
    Discover our top product SMYD2A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
    别名
    SMYD2 (SMYD2A 产品)
    别名
    HSKM-B antibody, KMT3C antibody, ZMYND14 antibody, 1110020E07Rik antibody, 4930402C15 antibody, Zmynd14 antibody, smyd2-a antibody, im:7146196 antibody, smyd2 antibody, wu:fc02f02 antibody, zgc:110553 antibody, si:dkey-121j17.3 antibody, zgc:136609 antibody, SET and MYND domain containing 2 antibody, SET and MYND domain containing 2 S homeolog antibody, SET and MYND domain containing 2a antibody, SET and MYND domain containing 2b antibody, SMYD2 antibody, Smyd2 antibody, smyd2.S antibody, smyd2a antibody, smyd2b antibody
    背景

    Synonyms: KMT3C, HSKM-B, ZMYND14, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, SMYD2

    Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

    基因ID
    56950
    UniProt
    Q9NRG4
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