FOLR2 抗体
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北京 101111
Quick Overview for FOLR2 抗体 (ABIN2800693)
抗原
See all FOLR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-FOLR2 Purified
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特异性
- The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.
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无交叉反应
- 小鼠
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交叉反应 (详细)
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- BW5147alpha,beta- cells
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亚型
- IgG1
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应用备注
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Western blotting: Non-reducing conditions.
Flow cytometry: Recommended dilution: 1-4 μg/mL -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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别名
- FOLR2
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背景
- Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1
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基因ID
- 2350
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UniProt
- P14207
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途径
- Dicarboxylic Acid Transport
抗原
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