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SIGLEC6 抗体 (N-Term)

This anti-SIGLEC6 antibody is a 兔 多克隆 antibody detecting SIGLEC6 in WB. Suitable for 人.
产品编号 ABIN2798979
发货至: 中国

Quick Overview for SIGLEC6 抗体 (N-Term) (ABIN2798979)

抗原

See all SIGLEC6 抗体
SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

适用

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宿主

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克隆类型

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多克隆

标记

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This SIGLEC6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 10-40, N-Term

    原理

    Rabbit Anti-Human SIGLEC6 (N-term) Antibody

    免疫原

    This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human SIGLEC6.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000Western blot analysis of SIGLEC6 Antibody (N-term) was detected using the purified Pab.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

    别名

    SIGLEC6

    背景

    Target Description: SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.

    Gene Symbol: SIGLEC6

    分子量

    49913 Da

    基因ID

    946

    UniProt

    O43699
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