SIGLEC6 抗体 (N-Term)
Quick Overview for SIGLEC6 抗体 (N-Term) (ABIN2798979)
抗原
See all SIGLEC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-40, N-Term
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原理
- Rabbit Anti-Human SIGLEC6 (N-term) Antibody
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免疫原
- This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human SIGLEC6.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of SIGLEC6 Antibody (N-term) was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
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别名
- SIGLEC6
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背景
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Target Description: SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.
Gene Symbol: SIGLEC6
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分子量
- 49913 Da
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基因ID
- 946
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UniProt
- O43699
抗原
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