TNNI2 抗体 (N-Term)
Quick Overview for TNNI2 抗体 (N-Term) (ABIN2798893)
抗原
See all TNNI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30, N-Term
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原理
- Rabbit Anti-Human TNNI2 (N-term) Antibody
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免疫原
- This TNNI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from human skeletal muscle tissue lysate, using TNNI2 Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- TNNI2 (Fast Skeletal Troponin I (TNNI2))
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别名
- TNNI2
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背景
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Target Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Gene Symbol: TNNI2
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分子量
- 21339 Da
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基因ID
- 7136
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UniProt
- P48788
抗原
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