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Recoverin 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects Recoverin in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN2798878
发货至: 中国
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Quick Overview for Recoverin 抗体 (C-Term) (ABIN2798878)

抗原

See all Recoverin (RCVRN) 抗体
Recoverin (RCVRN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Recoverin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 169-200, C-Term

    原理

    Rabbit Anti-Human Recoverin (C-term) Antibody

    免疫原

    This Recoverin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-200 amino acids from the C-terminal region of human Recoverin.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100The anti-Recoverin C-term Pab is used in Western blot to detect Recoverin in Y79 cell lysate.
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    Recoverin (RCVRN)

    别名

    Recoverin

    背景

    Target Description: Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.

    Gene Symbol: RCVRN

    分子量

    23130 Da

    基因ID

    5957

    UniProt

    P35243

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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