Recoverin 抗体 (C-Term)
Quick Overview for Recoverin 抗体 (C-Term) (ABIN2798878)
抗原
See all Recoverin (RCVRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 169-200, C-Term
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原理
- Rabbit Anti-Human Recoverin (C-term) Antibody
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免疫原
- This Recoverin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-200 amino acids from the C-terminal region of human Recoverin.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100The anti-Recoverin C-term Pab is used in Western blot to detect Recoverin in Y79 cell lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- Recoverin (RCVRN)
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别名
- Recoverin
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背景
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Target Description: Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.
Gene Symbol: RCVRN
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分子量
- 23130 Da
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基因ID
- 5957
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UniProt
- P35243
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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